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Breast Cancer Information |
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Breast Cancer Screening
Breast cancer is the second most common cancer women face second only to lung cancer, however it is the most feared cancer or disease for most women. It occurs in about 12% of women who will live to the age of 90. Several well established factors increase the risk of breast cancer and they include family history, nulliparity (not having had children), early menarche (starting menstrual cycles early), advanced age and a personal history of breast cancer. Other risks include exposure to environmental toxins such as tobacco smoke that increase the chance for cancer growth. October is Breast Cancer Awareness Month. The American Cancer Society has many activities this month to bring this to the public attention. Early education on self-breast exam and early screening is extremely important in achieving good outcomes. Self-exam and physician examination will detect cancer at a rate between 70 - 80%. Adding screening mammography (mammograms) will increase detection to 96 - 98%. It has been shown that early detection through clinical exam and mammography can reduce breast carcinoma mortality by 20 to 30%. Today's gold standard for screening (mammograms) will still miss between 10 and 15% of neoplasm. Therefore, if a clinically noted mass is followed by a negative mammogram the work up should then include a breast ultrasound and/or a fine needle aspiration cytology and close interval examinations. The modality of Magnetic Resonance Imagining (MRI) is a method of examining the breasts that is far more sensitive in picking up smaller tumor than Mammogram. MRI is widely used in Europe but has not taken on in the US yet. It is more expensive as a screening tool in the USA, but since it is so widely used in Europe it is actually less expensive there. Even with open biopsies of suspicious masses the diagnosis of a malignancy is one in about five biopsies performed. This may seem costly but the morbidity and mortality of missing a malignancy is even more so. Screening should start with a baseline mammogram at age 35, or younger if there is a strong family history. Annual examinations should be performed once a woman reached 40 years of age, and self examination should be encouraged monthly starting at the age of twenty. Disease prevention & early screenings is the mainstay of a preventive medical practice despite the somewhat conservative recommendations made by medical specialty societies and the managed care industry. Oftentimes the risk-benefit ratio for cancer screening has the dollar as it's bottom line, but if you are the unfortunate patient to have a cancer that was not detected early, then all the statistics in the world will not matter to you. My philosophy is to pay a little more in time and money upfront to assure a disease free state. An important thing for women to remember is a positive family history alone increased lifetime risk of cancer to about 25%, that is double the incidence of no such history. Recently the interest has focused on cancers associated with germ line (inherited) genetic mutations. While approximately 5 - 10% of all breast cancer sufferers have a mutation in BRCA1 gene (located on chromosome 17) and BRCA2 gene (located on chromosome 13), this type of screening should only be done when a first degree relative with know cancer and a positive mutation is detected or whether a women falls into a certain ethnic group. Women who have inherited a BRCA1 or BRCA2 mutation have a relatively high lifetime risk of breast cancer (about 50-85%). Risk for cancer in the opposite breast of a woman with a BRCA1 mutation is about 25%. In such cases genetic screening may be advocated. Once a tumor is detected important prognostic determiners as stage of the disease, histology and nuclear grade, estrogen and progesterone receptor status and HER2/neu gene amplification tests are advisable. For more information on Breast Cancer the following websites are helpful: http://cancerweb.ncl.ac.uk/cancernet/ and www3.cancer.org/cancerinfo. Also a call to the American Cancer Society at (800) ACS-2345 can be of help. To conclude, it is extremely important for women to maintain annual physical exams and aggressive cancer screening regiments. There are means to help prevent cancer in those women who seem predisposed. Screening is one thing, but taking measures to help prevent cancer growth is yet another. There are things women do on a daily basis that can increase their chances for breast cancer (and other cancers) that they are not aware. The programs advocated at my center are based on lifestyle modification, prevention, early detection, natural hormone replacement and nutritional medicine. Women should take a proactive approach to the breast cancer issue, for it may save their lives. This topic is one that is close to my heart, as my ex-wife is a breast cancer survivor. Breast Cancer Screening and Prevention JP Saleeby, MD is Assistant Medical Director of the Emergency Room at LRMC, Hinesville, GA. He hold adjunct professorship in the School of Nursing at Georgia Southern University. He performs online telemedicine consultation via http://www.saleeby.net
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Six Steps to Reduce Your Risk of Breast Cancer 11/21/08
by: Kim Beardsmore
We hear it all the time…lose weight for your health. Few people however, realize the extent to which this is critical to their physical well-being and ultimately their life expectancy.
In January 2003, the Journal of the American Medical Association featured a study finding that obesity appears to lessen life expectancy, especially among young adults. The researchers compared Body-Mass Index (BMI) to longevity and found a correlation between premature death and higher BMIs. For example, a 20-year-old white male, 5’10” weighing 288 pounds with a BMI of greater than 40 was estimated to lose 13 years of his life as a result of obesity.Jamie McManus, M.D., F.A.A.F.P. and author of “Your Personal Guide to Wellness” notes that while this study referenced extreme levels of obesity, there are still millions of overweight people in developed countries with a life expectancy rate that is three to five years less than their healthy-weight counterparts. She also estimates that there are 600,000 obesity related deaths each year in America.
Just how does obesity shorten our lifespan? The answer to this question is complex, yet there is a clear link between obesity and the development of cancer. An extensive study conducted by the American Cancer Institute involving 750,000 people showed that obesity significantly increased the risk of cancer developing in the following organs: breast, colon, ovaries, uterus, pancreas, kidneys and gallbladder.
Michael Thun, MD, vice-president of epidemiology and surveillance research for the American Cancer Society (ACS) says one reason obesity may raise cancer risk is because fat cells produce a form of estrogen called estradiol that promotes rapid division of cells, increasing chances of a random genetic error while cells are replicating, which can lead to cancer. In addition, fat centered around the abdomen may increase insulin and insulin-like growth factors in the blood, which may increase cancer risk.
"Women who are obese after menopause have a 50% higher relative risk of breast cancer," notes Thun, "and obese men have a 40% higher relative risk of colon cancer…. Gallbladder and endometrial cancer risks are five times higher for obese individuals”.There is evidence that cancer rates in developed countries are increasing at 5 to 15 times faster than developing countries. A major contributor to this alarming reality has proven to be diet. In populations where the diet consists mostly of fresh fruit and vegetables and whole grains – in contrast to the typical Western diet of fatty meats, refined flours, oils and sugars – the risk of cancer is much lower.
The interaction of diet and the development of cancer is an active field of research and Dr David Heber, M.D., Ph.D. and author of “What Color is Your Diet”, says “It appears that diet has its most significant effects after the cancer has already formed, acting to inhibit or stimulate the growth of that cancer”. At the risk of oversimplifying a complex set of interactions, the typical Western diet that leads to obesity may actually act to stimulate the growth of cancer cells.It is never too late to improve your health through healthful eating and adopting a more health-giving lifestyle. Here are simple steps to follow which can make an immediate improvement to your health and vitality.
Being overweight or obese has been identified next to smoking, as the most preventable major risk to developing cancer. Even small weight losses have been shown to have beneficial health effects. So it’s never to late to start and you can never be too young or too old to be concerned about your health and do something about achieving a more healthy weight.
(c) Copyright by Kim Beardsmore
About The Author
Kim Beardsmore is successful a weight loss coach who will cut through the diet-hype and ensure you find consistent results: week in, week out.You will learn how to stabilize at your goal weight and never 'diet' again. No public 'weigh-ins', meetings that cost you money or fads...simply long term results. You can receive a free, no obligation consultation. Visit: http://leanmachine.org/?refid=bc-27546.
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